Case studies: the new cancer drug trial

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The Observer,
Sunday August 10 2008
Article history
Almost 800 terminally ill cancer patients already participate in clinical trials being run by the 19 experimental cancer medicine centres.
They are people whose NHS treatment has either not worked or stopped working. Each trial involves patients taking either an experimental drug, or an existing treatment usually used in other cancers, or a standard chemotherapy drug taken with either an unlicensed or established drug.Unlike some other clinical trials, these patients are not paid. They take part to give themselves a chance of extra life, to help future generations of cancer sufferers and also to involve them in something positive at an otherwise depressing time.

Case study 1
'If there's a bit of hope, there's life'
Ruth Potts counsels cancer patients and their families at Belfast City Hospital. The 56-year-old was diagnosed with ovarian cancer in April 2007
When my doctors recently offered me the chance to join an experimental cancer trial, I asked: "Will this extend my life?" They said: "It might." So I agreed. I was keen to try anything that might help me because my ovarian cancer had returned after I'd been in remission for nine months, which was devastating. Continue in The Guardian...

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Mesothelioma & Asbestos Awareness Center Hails Effects Of Breakthrough Drug Combination For Elderly Pleural Mesothelioma Patients

Alimta and Paraplatin combination found to be especially successful in older mesothelioma sufferers

Syracuse, New York 8/05/2008 07:24 PM GMT (FINDITT)

An Italian study involving the effectiveness of Alimta (pemetrexed) and Paraplatin (carboplatin) was revealed at the 12thWorld Conference on Lung Cancer in 2007 and recently published in the British Journal of Cancer in June of this year. The study states that this combination of drugs is highly effective in pleural mesothelioma patients aged 65 or older.

Pleural mesothelioma is a fatal type of cancer affecting the pleural lining of the lungs. It is conclusively caused by prior exposure to asbestos. Pleural mesothelioma has a latent period of between twenty and fifty years, and the majority of individuals who receive a mesothelioma diagnosis are between the ages of 50 and 70 years old. The survival rate associated with pleural mesothelioma is less than one percent, and most mesothelioma sufferers will unfortunately surrender to this aggressive form of cancer in less than two years following their initial diagnosis.

The Alimta and Paraplatin duo has a one-year survival rate of over 60% and is very effective in older mesothelioma patients, with a median survival rate at about 14 months for individuals in the older age group (age 70 or older) as opposed to a survival rate of 11 months in participants in the younger age group.

There is presently no known cure for pleural mesothelioma. However, various mesothelioma treatment methods, including chemotherapy and other drug combinations, may control the disease and lessen the presence of mesothelioma symptoms in patients.

The Mesothelioma & Asbestos Awareness Center acknowledges the combination of Alimta and Paraplatin as an effective method of mesothelioma treatment and expresses the ongoing urgency for increased funding for mesothelioma-related studies and research.

The Mesothelioma & Asbestos Awareness Center is the web’s leading resource for information related to asbestos exposure....

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Veterans of the US armed forces after they had been diagnosed with Mesothelioma.

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(PRWEB) August 4, 2008 -- Mesothelioma victims, or individuals who have been diagnosed with mesothelioma are encouraged to call the Msecothelioma Victims Center for free help and assistance, related to this lethal form of cancer at 866-714-6466. Americas Watchdog created the Mesothelioma Victims Center after it discovered there was no safety net for US citizens, US Navy veterans or veterans of the US armed forces after they had been diagnosed with mesothelioma. According to Americas Watchdog, "upon receiving the news of a mesothelioma diagnosis, a victim or their family should first call the Mesothelioma Victims Center for more than just free advice. We have created a free world class service for mesothelioma victims that includes information about who are the best mesothelioma law firms in the country, assistance with VA or Social Security disability benefits, healthcare options, etc. We know first hand, because it happened to our family". Mesothelioma victims or their family members can call the Mesothelioma Victims Center anytime at 866-714-6466 or visit their web site at

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